Abstract: Carbon Capture, Utilization and Storage(CCUS) is the key technology to achieve carbon emission reduction. Due to the influence of formation conditions and long-term storage characteristics, there is a risk of CO₂ leakage during geological storage. Based on the investigation of domestic and foreign literature, the research progress of CCUS sequestration leakage is reviewed. CO₂ is mainly sequestration in geological bodies through structural sequestration, residual gas sequestration, dissolution sequestration and mineral sequestration. Under the conditions of injection and storage, the leakage channels can be summarized as wellbore leakage, cap penetration and diffusion, and fault leakage. Among them, the main causes of wellbore integrity failure are micro-annulus in the first cementing surface caused by the sudden drop in wellbore temperature during injection and chemical corrosion during long-term wellbore service. The local high pressure caused by the accumulation of CO₂ at the bottom of the cap layer due to buoyancy will lead to the infiltration and diffusion of CO₂ along the cap layer. The change of reservoir stress state after injection and the activation fault caused by water-rock chemical reaction are the main channels for leakage along the fault. Leakage hazards include human health threats and ecological environment impacts. Leakage monitoring methods are divided into three categories: underground, near-surface and atmosphere. Research on CCUS wellbore leakage is very limited at present, especially the quantitative research on the failure mechanism, influencing factors and control methods of wellbore seal integrity in injection wells.